Andrew Wheeler has had a long career working on environmental issues in both government and private sectors. He began his career during the George H. W. Bush Administration as a special assistant in EPA's Pollution Prevention and Toxics office. Wheeler was a principal and the team leader of the Energy and Environment Practice Group at FaegreBD Consulting, as well as Counsel at Faegre Baker Daniels law firm, where he practiced since 2009. He also served as the firm’s co-chair of the Energy and Natural Resources Industry team.

Prior to his work with the firm, Wheeler served for six years as the majority staff director and chief counsel, as well as the minority staff director, of the Senate Committee on Environment and Public Works. Before his time at the full Senate EPW Committee, he served in a similar capacity for six years for the Subcommittee on Clean Air, Climate Change, Wetlands and Nuclear Safety. Wheeler is the past chairman of the National Energy Resource Organization (NERO), a Stennis Fellow, and an eagle scout.

He was born in Hamilton, Ohio and completed his law degree at Washington University in St. Louis, his MBA at George Mason University, and his undergraduate work at Case Western Reserve University in English and Biology.